Prostatic fluid immunoglobulin A, M, G, E in chronic prostatitis sufferers

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dc.contributor.authorBayraktar, Vasyl M.en
dc.contributor.authorБайрактар, Василь Миколайовичuk
dc.date.accessioned2025-06-13T17:02:18Z
dc.date.available2025-06-13T17:02:18Z
dc.date.issued2025
dc.description.abstractImmunoglobulins reach the secretion, where the plasma cells are located, whether immunoglobulins are antigen-specific and where activation of the adaptive immune response. Immune cells, were scattered in the stroma and not organized mucosae-associated lymphoid-tissue. IgA immunostaining identified stromal plasma cells and epithelial cells in non-immunized rats. Injected tetramethylrhodamine - IgA transcytosed the epithelium along with polymeric immunoglobulin receptor. An increased number of dendritic cells that cooperate in other sites with transient immunocompetent lymphocytes, and the higher levels of interleukin-1β, interferon-γ and transforming growth factor-β, explain the levels of specific antibodies. Nasal immunization produced similar results except for the increase in dendritic cells. This immunomodulatory strategy seems useful to boost immunity against genitourinary infections and, perhaps, cancer. IgA and IgG are part of the many components of the prostate gland secretion, and correspond to 0.1 and 0.05 mg/mL of the seminal fluid, respectively. IgA and IgG were initially identified in association with the prostate secretion within the lumen of human prostate biopsy samples, by immunofluorescence. The variation in IgA content in the prostatic fluid and serum in chronic prostatitis led to the assumption of the non-systemic character of prostate immunity. Infections of the urogenital tract and chronic prostatitis result in the presence of IgA in the prostatic fluid and in higher titers of bacteria-specific antibodies in the prostate secretion as compared to the serum, in some conditions. Production of specific antibodies in the absence of local infection. In addition, it is not known whether this possibility may be related to the fact that most cases of prostatitis are not directly associated with the presence of an infectious agent.en
dc.identifier.citationBayraktar V. M. Prostatic fluid immunoglobulin A, M, G, E in chronic prostatitis sufferers / V. M. Bayraktar // Українська школа ендокринології : матеріали наук.-практ. конф. (Харків, 5–6 черв. 2025 р.). – Харків : ДУ ІПЕП, 2025. – С. 8–10.en
dc.identifier.urihttps://dspace.onu.edu.ua/handle/123456789/41689
dc.language.isoen
dc.publisherІнститут проблем ендокринної патології ім. В. Я. Данилевського Національної академії медичних наук Україниuk
dc.subjectimmunoglobulinen
dc.subjectIgAen
dc.subjectIgMen
dc.subjectIgGen
dc.subjectIgEen
dc.subjectchronic prostatitisen
dc.subjectherpes simplex virusen
dc.subjectChlamydia immunoglobulinsen
dc.titleProstatic fluid immunoglobulin A, M, G, E in chronic prostatitis sufferersen
dc.typeArticleen
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