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Документ The antibiotic influence on antagonistic activity of microorganisms that are the base of some probiotics(Одеський національний університет імені І. І. Мечникова, 2020) Lazar, A.; Sarova, N.; Rusakova, Mariia Yu.; Русакова, Марія Юріївна; Русакова, Мария ЮрьевнаThe work was devoted to the study of the strain interactions that isolated from probiotics with some opportunistic pathogens. In the co-cultivation of L. sporogenes and B. clausii probiotic strains, obtained from "Lactovit Forte" and "Enterogermina" preparations and strains of E. coli ATCC 25922 and S. aureus ATCC 25923, an antagonistic interaction was determined. The addition of 0.0313 mg/ml of ciprofloxacin enhanced the antagonistic interaction between probiotic strains, in particular B. clausii and cultures of E. coli ATCC 25922 and S. aureus ATCC 25923.Документ The characteristics of microbial interaction between some representatives of human microbiota and probiotic strains(Одеський національний університет імені І. І. Мечникова, 2020) Sarova, N.; Lazar, A.; Rusakova, Mariia Yu.; Русакова, Марія Юріївна; Русакова, Мария ЮрьевнаThe work was dedicated to the study of the interaction of strains isolated from probiotics, with some opportunistic microorganisms. It has been established that between L. acidophilus, L. sporogenes, B. clausii and the opportunistic strains (Candida albicans ATCC 18804, Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 25923) antagonistic, neutral and mutual interactions develop. Over time, the form of interaction may change. The most effective, stable antimicrobial effect caused by the biologically active exometabolite production was determined for L. acidophilus to all investigated test microorganisms.