Репозитарій ОНУ імені І.І.Мечникова

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Fractal microscope for direct virus-cell interaction Monitoring
(Одеський національний університет імені І. І. Мечникова, 2004) Fedchuk, Oleksandr P.; Fedchuk, A. O.; Fedchuk, A. S.; Shitikova, L. I.; Fedchuk, P. O.
The fractal type of natural science laws’ understanding has become the leading one in biomedical research, especially in the last two decades. It takes start from the entropy based proof of the necessity of living cell to divide in order to survive. The Fourier t ran s form of the sensitive cell subs tra te was formed through laser diffraction patterning and used as the reference data. It was shown that each specimen could be marked with fractal dimension D which could be changed only in the process of non-equilibrium fractal growth and could serve as laboratory research identifier. It was shown experimentally that the viral particles attacking the sensitive substrate changes the D value at every stage of virus-cell interaction. All the mentioned features of the proposed fractal approach to the problem of virus-cell interaction makes it to be attractive and useful laboratory/clinical express-tool for the purposes of antiviral research, antiviral drug testing and clinical research. BACKGROUND