Tereshchenko, Alla V.Fedorenko, V.Smyntyna, Valentyn A.Konup, Ihor P.Konup, A.Eriksson, M.Yakimova, R.Ramanavicius, A.Balme, S.Bechelany, MikhaelКонуп, Ігор ПетровичКонуп, Игорь ПетровичТерещенко, Алла ВолодимирівнаТерещенко, Алла Владимировна2017-10-302017-10-302016Advances in Bioelectrochemistry and Nanomaterials [Электронный ресурс] : book of abstracts of the 9th Nanoconference (20th-22nd October 2016) / Vilnius University (VU) . – Электрон. кн. – Vilnius, 2016https://dspace.onu.edu.ua/handle/123456789/11218Optical immunosensor for the determination of Grapevine virus A-type (GVA) proteins (GVAantigens) has been developed [1]. The immunosensor was based on thin films of ZnO (100 nm thickness) formed by atomic layer deposition (ALD). The ZnO-based films have demonstrated good surface-structural properties for the absorption of antibodies (anti-GVA) against GVAantigens in order to form a biosensitive layer. The absorption of anti-GVA antibodies resulted in new photoluminescence band appearance in the region of 400-550 nm that can be caused by the formation of some chemical bounds during the anti-GVA adsorption on ZnO surface [2]. The possibility to detect GVA-antigens without additional labels (e.g enzymes or fluorescent dyes) has been demonstrated. The GVA-antigen detection was performed by the evaluation of changes and behavior of the photoluminescence band, related to protein adsorption (Fig. 1). The sensitivity of as-formed label-free biosensor towards the GVA-antigens was determined in the range from 1 pg/ml to 10 ng/ml; in addition, the selectivity of biosensor was evaluatedukoptical immunosensorGrapevine virus A-type (GVA)thin films of ZnOOther