Bayraktar, Vasyl M.Байрактар, Василь Миколайович2025-05-272025-05-272025Bayraktar V. M. Toxicity reduce in Chlamydophila psittaci before to producing chlamydial immunogen biopeptide conjugated vaccine / V. M. Bayraktar // From experimental and clinical pathophysiology to the achievements of modern medicine and pharmacy : collected papers of 7th scientific and practical conference of students and young scientists with international participation (Kharkiv, 15 May 2025). – Kharkiv : NUPh, 2025. – P. 17–20.https://dspace.onu.edu.ua/handle/123456789/41547Chlamydiae are obligate intracellular parasites responsible for various acute and chronic diseases in animals and humans. The outer membrane of the Chlamydial cell wall contains a truncated lipopolysaccharide (LPS) antigen, featuring a group-specific epitope composed of a trisaccharide of 3-deoxy-D-manno-oct-2-ulosonic (Kdo). Chlamydia trachomatis infection in men may manifest as epididymitis, orchiepididymitis, vesiculitis, orchitis, cooperitis, prostatitis, urethritis, paraurethritis. Clinical symptoms include mucous discharge from the urethra, weakness, fever and general malaise, presence of blood in semen, discomfort during urination, lower back pain and pain in the urethra and testicles.enChlamydophila psittacicell cultureDEAE-Dextrancultivationultra violetirradiationvaccine developmentToxicity reduce in Chlamydophila psittaci before to producing chlamydial immunogen biopeptide conjugated vaccineArticle