Zinchenko, Oksana Yu.Shmatkova, Natalya V.Seifullina, Inna Y.Kovtalo, M. S.Prodanets, N.Сейфулліна, Інна ЙосипівнаСейфуллина, Инна ИосифовнаЗинченко, Оксана ЮрьевнаЗінченко, Оксана Юріївна2017-12-122017-12-122015Actual problems of microbiology and biotechnology: abstracts of the international conference for young scientists (june 1st - 4th, 2015) / chairman: V. O. Ivanytsia; Odessa І.І. Mechnikov National Univ. – Odesa, 2015.https://dspace.onu.edu.ua/handle/123456789/11939Extended-spectrum beta-lactamase-producing Escherichia coli are an increasingly significant cause of hospital and community acquired infections. One of the ways to overcome the resistance based on lactamase production is the combined use of antibiotics and β-lactamase inhibitors. Unfortunately the spectrum of existing inhibitors is rather limited. Thereby the screening of new classes of compounds for their potential inhibitory activity towards β-lactamase enzymes is a perspective direction of research.enEscherichia coliβ-lactamase enzymesnicotinic acid derivativesArticle