PSEUDOMONAS AERUGINOSA BIOFILM GROWTH DYNAMIC IN PRESENCE OF PORPHYRINS BISMUTH COMPLEXES

Abstract

Biofilm formations is a one of most important processes that provide potential pathogenic bacteria such as Pseudomonas aeruginosa to cause human diseases and to be resistant to the numerous of antimicrobial drugs. Bacterial biofilms characterize with unique difficult structures and process of its formation fallow in some consistent stages. All of these stages from adgesion of bacterial cells to decomposition of an old biofilms characterize with some biological processes and time intervals. Biofilm formation of P. aeruginosa begin in laboratory conditions after 15 minutes of incubation and live of this pathogen biofilms continue up to 18 days. Even in the earlier stages of this process, biofilms completely separates from planktonic culture, dynamics and live time of which is very distinguish from biofilms.