Sensitivity to ciprofloxacin of Pseudomonas aeruginosa strains with different levels of C-DI-GMP biosynthesis
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Дата
2017
Науковий керівник
Укладач
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Назва тому
Видавець
Odessa I. I. Mechnikova National University
Анотація
It was investigated the antibiotics sensitivity of Pseudomonas
aeruginosa strains with different levels of c-di-GMP biosynthesis: PA01
Δ 100 wspF1 (increased biosynthesis level) and PA01 pJN2133 (low
level of biosynthesis) in comparison with the collection P. aeruginosa
strains: РА01 and ATСС 27853. Not established significant differences
between the strains sensitivity to ciprofloxacin. It is shown that the
minimum concentration of ciprofloxacin that inhibit biofilm formation
is significantly lower than minimum inhibitory concentrations of P.
aeruginosa growth. It is established that subinhibitory concentrations of
ciprofloxacin violates the biofilms morphology.
Опис
Ключові слова
biofilm, Pseudomonas aeruginosa, ciprofloxacin, antibiotic sensitivity, minimum inhibitory concentration
Бібліографічний опис
International conference of young scientists "Modern problems of microbiology and biotechnology", Odesa, Ukraine, June 20-24, 2017