Please use this identifier to cite or link to this item: http://dspace.onu.edu.ua:8080/handle/123456789/10928
Title: Sensitivity to ciprofloxacin of Pseudomonas aeruginosa strains with different levels of C-DI-GMP biosynthesis
Authors: Semenets, Anastasiia S.
Lisova, O. O.
Filipova, Tetiana O.
Citation: International conference of young scientists "Modern problems of microbiology and biotechnology", Odesa, Ukraine, June 20-24, 2017
Issue Date: 2017
Publisher: Odessa I. I. Mechnikova National University
Keywords: biofilm
Pseudomonas aeruginosa
ciprofloxacin
antibiotic sensitivity
minimum inhibitory concentration
Abstract: It was investigated the antibiotics sensitivity of Pseudomonas aeruginosa strains with different levels of c-di-GMP biosynthesis: PA01 Δ 100 wspF1 (increased biosynthesis level) and PA01 pJN2133 (low level of biosynthesis) in comparison with the collection P. aeruginosa strains: РА01 and ATСС 27853. Not established significant differences between the strains sensitivity to ciprofloxacin. It is shown that the minimum concentration of ciprofloxacin that inhibit biofilm formation is significantly lower than minimum inhibitory concentrations of P. aeruginosa growth. It is established that subinhibitory concentrations of ciprofloxacin violates the biofilms morphology.
URI: http://dspace.onu.edu.ua:8080/handle/123456789/10928
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