The anti-candida activity of new n-methylquinolinyl- porphyrins in vitro
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Дата
2017
Науковий керівник
Укладач
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Видавець
Odessa I. I. Mechnikova National University
Анотація
The activity of new N-methyl-quinolinyl-porphyrins against
different morphological forms of Candida albicans (unattached, freedividing
cells, as well as structures formed in the process of biofilm
maturation) was characterized. Modification of porphyrin molecules by
N-methyl-6-quinolinyl increases the fungicidal effect on the yeast cells,
in contrast to N-methyl-7-quinolinyl derivatives that are effective against
hyphal structures. Candida albicans biofilm cells are more resistant to
low concentrations of the studied compounds.
Опис
Ключові слова
Candida albicans, biofilm, planktonic cells, porphyrin
Бібліографічний опис
International conference of young scientists "Modern problems of microbiology and biotechnology", Odesa, Ukraine, June 20-24, 2017