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http://dspace.onu.edu.ua:8080/handle/123456789/10925
Title: | The anti-candida activity of new n-methylquinolinyl- porphyrins in vitro |
Authors: | Ovchinnikov, S. Vasyil'yev, M. Rusakova, Mariia Yu. Русакова, Мария Юрьевна Русакова, Марія Юріївна |
Citation: | International conference of young scientists "Modern problems of microbiology and biotechnology", Odesa, Ukraine, June 20-24, 2017 |
Issue Date: | 2017 |
Publisher: | Odessa I. I. Mechnikova National University |
Keywords: | Candida albicans biofilm planktonic cells porphyrin |
Abstract: | The activity of new N-methyl-quinolinyl-porphyrins against different morphological forms of Candida albicans (unattached, freedividing cells, as well as structures formed in the process of biofilm maturation) was characterized. Modification of porphyrin molecules by N-methyl-6-quinolinyl increases the fungicidal effect on the yeast cells, in contrast to N-methyl-7-quinolinyl derivatives that are effective against hyphal structures. Candida albicans biofilm cells are more resistant to low concentrations of the studied compounds. |
URI: | http://dspace.onu.edu.ua:8080/handle/123456789/10925 |
Appears in Collections: | Статті та доповіді БФ |
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