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Title: Amixin effect on different strains of Pseudomonas aeruginosa which have different abilities for biofilm formation
Authors: Kladnitskii, V. Y.
Halkin, Mykola B.
Citation: International conference of young scientists "Modern problems of microbiology and biotechnology", Odesa, Ukraine, June 20-24, 2017
Issue Date: 2017
Publisher: Odessa I. I. Mechnikova National University
Keywords: Pseudomonas aeruginosa
Abstract: The study of how tilorone in different concentrations interact with collection strains of Pseudomonas aeruginosa, which have different ability to form the biofilm was performed. For the experiment were prepared five dilutions of tilorone 25, 50, 100, 250 and 500 mcg/ml. To determine the effect of tilorone on the biofilm formation used method for cultivation of the biofilms in the plates for cell culture, using the medium LB. The presence of the biological activity of the compounds judged by the presence of optical density difference between the experimental and control samples. The results showed that the different concentrations of test compound act differently on growth and biofilm formation of test strains Pseudomonas aeruginosa, causing stimulation or inhibition, or nothing changes at all.
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